Alcohols and polyols
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- (1)
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- (30)
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- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (61)
- (13)
- (14)
- (1)
- (2)
- (1)
- (26)
- (6)
- (4)
- (1)
- (6)
- (1)
- (462)
- (9)
- (46)
- (11)
- (45)
- (6)
- (1)
- (7)
- (10)
- (145)
- (114)
- (6)
- (5)
- (1)
- (1)
- (1)
- (1)
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- (1)
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- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
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- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (2)
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- (1)
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- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (2)
- (5)
- (4)
- (33)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (17)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
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- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (7)
- (4)
- (1)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
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- (11)
- (14)
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- (2)
- (1)
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- (2)
- (10)
- (1)
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- (1)
- (3)
- (5)
- (1)
- (1)
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- (1)
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- (1)
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- (9)
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- (2)
- (12)
- (4)
- (1)
- (1)
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- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (1)
- (1)
- (30)
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- (11)
- (82)
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- (1)
- (81)
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Filtered Search Results
Medchemexpress LLC Noscapine (hydrochloride) | 912-60-7 | 99.9% | 449.88 | 1 G
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Noscapine (hydrochloride) is an orally active phthalideisoquinoline alkaloid with potent antitussive properties. It activates sigma opioid receptors and acts as a non-competitive Bradykinin inhibitor. This compound also disrupts microtubule dynamics, induces mitotic arrest and apoptosis.
- Orally active phthalideisoquinoline alkaloid
- Potent antitussive properties
- Activates sigma opioid receptors and acts as a non-competitive Bradykinin inhibitor
- Disrupts microtubule dynamics, induces mitotic arrest and apoptosis
- Exhibits anticancer, neuroprotective, and anti-inflammatory activities
- Can cross the blood-brain barrier
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Clorgyline hydrochloride | 17780-75-5 | 99.9% | C13H16Cl3NO | 100 MG
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Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) used in scientific research. It is structurally related to Pargyline. It has little effect on the amounts of conjugated dopamine (DA) in superfusate of slices from rat striatum. It contains an Alkyne group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. This product is for research use only, not sold to patients.
- Irreversible and selective inhibitor of monoamine oxidase A (MAO-A)
- Used in scientific research
- Structurally related to Pargyline
- Has little effect on conjugated dopamine (DA) in superfusate of slices from rat striatum
- Contains an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Arg1-in-1 hydrochloride | 90.0% | C11H22BClN2O4 | 1 MG
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ARG1-IN-1 hydrochloride is an orally active arginase inhibitor with an IC50 value of 29 nM. It can inhibit serum arginase activity and increase arginine levels in mouse tumor models, making it applicable for tumor research.
- Orally active arginase inhibitor.
- Inhibits serum arginase activity.
- Increases arginine levels in mouse tumor models.
- Applicable for tumor research.
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Medchemexpress LLC BMY-25368 hydrochloride | 86134-36-3 | ≥97.0% | 379.88 | C19H26ClN3O3 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BMY-25368 hydrochloride is a research reagent used as a histamine H2 receptor antagonist and gastric acid secretion inhibitor. Supplied as a hydrochloride salt with documented molecular and purity data, it is intended for preclinical in vitro and in vivo studies where receptor antagonism or gastric secretion modulation is required.
- Histamine H2 receptor antagonist for gastric acid secretion studies.
- Hydrochloride salt form for improved solubility and stability.
- High purity (≥97.0% by NMR) suitable for research use.
- Verified molecular weight (379.88) and formula for accurate dosing.
- Available in small-scale quantities for preclinical experiments.
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Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 1 ML
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Flavoxate hydrochloride | 3717-88-2 | 99.7% | 1 ML
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Medchemexpress LLC SB-277011 (hydrochloride) | 215804-67-4 | 99.6% | 475.02 | 25 MG
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SB-277011 hydrochloride is a potent, selective, orally bioavailable, and brain-penetrant dopamine D3 receptor (D3R) antagonist. It demonstrates 80- to 100-fold selectivity over other dopamine receptors.
- Ki values of 10.7 nM and 11.2 nM at rodent and human D3R, respectively.
- Selectivity over D2, 5-HT1B, and 5-HT1D receptors.
- Oral bioavailability of 43% and a half-life of 2.0 h in rats.
- High brain-penetrant (brain:blood ratio of 3.6:1).
- Reverses quinelorane effects in the nucleus accumbens at 3 mg/kg (p.o.) in rats.
- Reduces intravenous cocaine self-administration in rats (12.5-25 mg/kg, i.p.).
- Inhibits basal and cocaine-enhanced locomotion in rats at 50 mg/kg.
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Medchemexpress LLC Alosetron hydrochloride | 122852-69-1 | MFCD03453647 | 99.6% | 10 MG
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Alosetron hydrochloride is a potent, selective 5-HT3 receptor antagonist provided for research use in studies of irritable bowel syndrome and visceral nociception. It is supplied as a high-purity solid and is also available as ready-to-use 10 mM solutions for laboratory assays.
- Potent and selective 5-HT3 receptor antagonist.
- Used in research on diarrhea-predominant irritable bowel syndrome and visceral nociception.
- High purity suitable for analytical and in vitro applications.
- Available as a solid and as pre-made 10 mM solutions for convenience.
- Characterization includes CAS 122852-69-1 and molecular weight 330.81 g/mol.
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Medchemexpress LLC Benzoic acid, 2-[4-[2-(1-piperidinyl)ethoxy]benzoyl]-, methyl ester, hydrochloride (1:1) | 1248-42-6 | 99.9% | 403.90 | 25 MG
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Pitofenone hydrochloride is a spasmolytic compound that inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and electric eel with Kis of 36 and 45 μM, respectively. It also exhibits anticonvulsant activity when combined with diclofenac and fenpivirine.
- Spasmolytic compound
- Inhibits acetylcholinesterase (AChE) activity
- Anticonvulsant activity in combination with diclofenac and fenpivirine
- Appearance: Solid
- Color: White to off-white
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Medchemexpress LLC Drofenine hydrochloride | 548-66-3 | 98.1% | 1 ML
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Drofenine hydrochloride is a potent competitive cholinesterase inhibitor. It acts as a BChE inhibitor with a Ki value of 3 μM and is intended for research use only.
- Potent competitive cholinesterase inhibitor
- BChE inhibitor
- Ki value of 3 μM
- Suitable for research use
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Medchemexpress LLC Nimustine hydrochloride (ACNU) | 55661-38-6 | 98.2% | 309.15 | 1 ML
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Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine. It functions as an alkylating agent by inducing DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), which activates the DNA damage response (DDR) signaling pathway. It also activates the p38 MAPK/JNK signaling pathway and demonstrates antitumor activity.
- Induces DNA double-strand breaks and inter-strand crosslinks.
- Activates DNA damage response signaling.
- Activates p38 MAPK/JNK signaling.
- Demonstrates antitumor activity.
- Exhibits cytotoxicity against human U87MG cells.
- Induces apoptosis in LN-229 cells.
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Medchemexpress LLC Amprolium (hydrochloride) | 137-88-2 | 98.8% | 1 ML
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Amprolium hydrochloride is provided as a 10 mM solution in 1 mL, with a purity of 98.8%. This product is intended for research use only and should be handled by qualified personnel in appropriately equipped facilities.
- 10 mM solution in 1 mL
- Purity: 98.8% (HPLC)
- Recommended storage: 4°C for sealed solutions, away from moisture
- For longer-term storage in solvent: -80°C for 6 months or -20°C for 1 month
- Can be shipped at room temperature if shipment duration is less than 2 weeks
- Intended for research applications
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Medchemexpress LLC Trazodone (hydrochloride) | 25332-39-2 | 99.6% | 50 MG
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This product is a triazolopyridine derivative, classified as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates antidepressant and anti-insomnia activities by antagonizing α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects. It is intended for research use only.
- Classified as a serotonin receptor antagonist and reuptake inhibitor (SARI)
- Exhibits antidepressant and anti-insomnia activity
- Antagonizes α1- and α2-adrenergic receptors
- Antagonizes histamine H1 receptors
- Minimal anticholinergic effects
- Purity of 99.60%
- Molecular formula: C19H23Cl2N5O
- Appears as a white to off-white solid
- Soluble in DMSO and water
- Binds to 5-HT1A receptor with high affinity
- Inhibits key signaling pathways for neuroinflammatory markers
- Increases BDNF and CREB expression
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Medchemexpress LLC Terazosin hydrochloride dihydrate | 70024-40-7 | 99.5% | 1 ML
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Terazosin hydrochloride dihydrate is a quinazoline derivative and a competitive, orally active α1-adrenoceptor antagonist. It functions by relaxing blood vessels and aiding in the opening of the bladder. This compound has potential applications in the treatment of benign prostatic hyperplasia (BPH) and high blood pressure. This product is for research use only.
- Competitive α1-adrenoceptor antagonist
- Relaxes blood vessels
- Aids in opening the bladder
- Potential for treating benign prostatic hyperplasia (BPH)
- Potential for treating high blood pressure
- Does not differentiate cloned α1-adrenoceptor subtypes
- Can promote stone discharge in the treatment of ureteral stones
- Reportedly safe and effective for distal ureteral stones, especially those >5 mm
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Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 g·mol⁻¹ | C21H26ClN | 500 MG
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Melitracen hydrochloride is an orally active tricyclic antidepressant research compound that inhibits norepinephrine and serotonin reuptake. Supplied as the hydrochloride salt, it is intended for in vitro and preclinical investigation of monoaminergic activity.
- Inhibits norepinephrine and serotonin reuptake, increasing monoamine availability.
- Provided as the hydrochloride salt for improved stability and solubility.
- High reported purity (≈99.8%) suitable for research applications.
- Molecular formula C21H26ClN, molecular weight 327.89 g·mol⁻¹.
- Soluble in DMSO and water at high concentrations with sonication.
- Recommended sealed storage away from moisture; short-term storage in solution at low temperatures.
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Medchemexpress LLC Articaine hydrochloride | 23964-57-0 | 99.4% | 500 MG
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Articaine hydrochloride is a selective inhibitor of voltage-gated sodium channels, exerting local anesthetic activity by inhibiting Na+ influx to block nerve impulse conduction. It also inhibits NF-κB activation and NLRP3 inflammasome pathways, demonstrating anti-inflammatory function. This compound is used in the study of dental local anesthesia and inflammatory-related diseases, such as acute kidney injury.
- Selective inhibitor of voltage-gated sodium channels (rNav1.4, hNav1.7, and rNav1.8)
- Inhibits Na+ influx to block nerve impulse conduction
- Exhibits local anesthetic activity
- Inhibits NF-κB activation and NLRP3 inflammasome pathways
- Demonstrates anti-inflammatory function
- Applicable in dental local anesthesia research
- Applicable in inflammatory-related diseases research, such as acute kidney injury
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